Product:

Complete Immuno D3

SKU: 1548
Supportive Function: Research is telling us that more people than not are deficient in vitamin D, and that we are not getting enough for optimal health. Vitamin D is quickly becoming known for its positive influences on immune system support (and support for autoimmune activity as well). This formula is boosted by other wellresearched immune ingredients, such as beta-sitosterol, probiotics, and quercetin.

When is Vitamin D and Synergistic Immune-Support helpful? For maintenance and optimal function of the immune system, and for autoimmune activity.
Clinical Applications Research: Vitamin D is a versatile nutrient. We’ve known for many years that vitamin D increases calcium absorption and helps develop strong bones and teeth, and that it is highly important for proper muscle function. However, vitamin D’s role in more diverse health-related issues has become apparent, such as inflammation (suspected to be at the root of many diseases), peripheral neuropathies, autism, heart activity, insulin resistance, polycystic ovarian syndrome (PCOS), depression, skin rejuvenation, brain health, dementia-related conditions, bone fracture repair, and many others. UV rays from the sun are necessary for synthesis of vitamin D in the skin, but many don’t get the sunlight exposure to maintain adequate vitamin D levels. Vitamin D deficiency is widespread, and in fact, it is estimated that half of all white and two thirds of all black adults have low D levels below 70 nm/L (Between 90-100 nmol/L is ideal). Blood levels of vitamin D can be raised with supplementation; ideally, the form used should be active vitamin D3 and not vitamin D2, which may not be as effective.

In recent years, in addition to all of the versatile uses for vitamin D, scientists have uncovered some of the profound effects that Vitamin D has on the immune system and autoimmune disorders. In particular, vitamin D positively affects T cell-mediated immunity and the dendritic cells (dendritic cells, or DCs, serve up foreign antigens on a silver platter to the T cells). Both Dr. Dan Murphy and Dr. Don Bellgrau have thoroughly researched vitamin D and its effects on the immune system; T cell immunity and dendritic cell immunotherapy are the primary areas of Dr. Bellgrau’s research.

Vitamin D and Dendritic Cells: Vitamin D has a very dramatic influence on these dendritic cells of the immune system, but why is this important? In the words of European Molecular Biology Organization scientists, “DCs are indispensable for the initiation of the primary immune response, but now it is well established that these cells are able to orchestrate the entire immune response, including the regulation of peripheral immune tolerance.”

Vitamin D and Immune Conditions: Vitamin D deficiency is associated with numerous immune conditions and diseases, and vitamin D supplementation is associated with beneficial effects in a multitude of conditions, from influenza to cancer/chemotherapy. Some of the immune conditions correlated to vitamin D intake include, but are not limited to: rheumatoid arthritis, multiple sclerosis, lupus (SLE), fibromyalgia, dermatological indications (i.e. psoriasis), diabetes type 1 and type 2, infectious disease and many others. Beta sitosterol is a phytosterol (a good plant fat), reported in the research to “possess anti-inflammatory, antipyretic, antineoplastic, and immune-modulating properties”; it has also “shown promise in normalizing Tcell function, dampening overactive antibody responses, and normalizing DHEA:cortisol ratios”.

Researchers also state that “commercial phytosterols may be of benefit in re-establishing optimal immune parameters. Restoring balance to the immune system may be of therapeutic benefit in disease processes such as chronic viral infections, stress-induced immune suppression, tuberculosis, allergies, cancer, rheumatoid arthritis and other autoimmune conditions”.  

Quercetin has potent immune properties, and has even been called by some “the most important flavonoid”. Quercetin has been named for its anti-inflammatory and antioxidant effects, and has been investigated for a wide range of potential health benefits.

The Journal of Immunology, June 15, 2010, describes dendritic cells as a major target for the control of harmful immune responses, and points out that quercetin reduced production of proinflammatory cytokine and chemokine signals. Additionally, researchers reported in the journal that quercetin “could be used in the prevention and therapy of chronic inflammation, autoimmunity, and transplantation”.

Lactobacillus Acidophilus, Lactobacillus Bifidus, and Lactobacillus Reuteri: Probiotics are not just for replacing imbalances caused by antibiotic drugs, they can be proactive in strengthening the immune system. A study published in Nutrition Research verifies this, and suggests that even the immune systems of healthy adults benefit from probiotic supplementation. A significant increase in the percentage of phagocytosing monocytes and neutrophils was observed over the trial period. Thus, the authors of this study concluded that, “nutritional supplementation with probiotics has the potential to improve innate immune function in healthy adults".

Interest in probiotics has been spurred on by the growing abundance of civilization disorders that include atherosclerosis, heart disease, hypertension and many others. Researchers of a peer-reviewed journal noted that, “probiotics are potentially capable of annihilating these disorders”. Additionally, lactobacillus reuteri administered in low doses has demonstrated a hypocholesterolemic effect both therapeutically and preventively.

REFERENCES AVAILABLE UPON REQUEST
Contraindications: Generally speaking, high dose vitamin D is becoming increasingly common (especially since many are deficient) with no side effects. Of all published cases of vitamin D toxicity for which a vitamin D amount is known, only one occurred at a level of intake under 40,000 IU per day. Caution is advised for sarcoidosis, hyperparathyroidism, and hypercalcemia, as vitamin D can raise calcium levels, which is considered a good thing unless levels are already high. It is probably prudent to take medications away from supplementation. Lab tests are always ideal to monitor individual situations.
Ingredients: Each Tablet Contains: Vitamin D3 (as cholecalciferol) 62 mcg. Proprietary blend 20.6 mg* of: Quercetin, Beta Sitosterol, Lactobacillus Acidophilus, Bifidobacterium Bifidum, Lactobacillus Reuteri.
Vegetarian: No
Suggested Dosage: One tablet daily or as directed.
Pack: 60 tablets
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