Product:

BP Renew

SKU: 2826
Supportive Function: BP Renew was formulated with strong nutrients and outstanding antioxidants to support lipid homeostasis, heart, arteries,kidneys, nervous system,and many other areas of the body.

When is BP Renew helpful? Lipid Homeostasis, Heart, Arteries, Artery Muscles Circulation, Vasoactivity, Blood Flow, Heart, Kidneys, Nervous System, Blood Sugar, Pollutant Detoxification, Stress, Healthy Aging, NOS (Nitric Oxide System), Angiotensin System, GABA Production, Water/Electrolyte Balance, Endothelial Function, Mitochondrial Function, Neurotransmitter Signalling, and any situation of oxidation since the combination of ingredients has outstanding antioxidant qualities.
Clinical Applications Research: Magnesium (as glycinate) is an essential mineral that has many roles, including co-factor for over 200 biochemical reactions, however one of the most important roles that magnesium plays is in the contraction-relaxation cycles of muscles. Calcium is essential mostly for the contraction phase, and magnesium is essential mostly for the relaxation phase. Magnesium is thus critical for proper muscle function, including the muscles that line our arteries and veins. In addition to working synergistically with calcium, magnesium helps to maintain the right balance of phosphates in the body; phosphates can be responsible for calcification of tissue (PLoS One. 2014 Dec 29;9(12):e116273. Magnesium … hyperphosphatemia in patients undergoing hemodialysis: a cohort study.Sakaguchi Y et al). Magnesium’s contribution to endothelial function and nerve function helps to maintain homeostasis of those cells (Johnson AC. Et al. Magnesium sulfate treatment…PLoS One. 2014 Nov 19;9(11):e113670). Magnesium is noted as one of the minerals that guards against oxidative damage to mitochondria and neuronal circuits associated with cognitive/affective behaviors (Du J. et al. The Role of Nutrients in Mitochondrial Function& Neurotransmitter Signaling… Crit Rev Food Sci Nutr.2014 Nov 3:0).

L-Taurine is an amino acid (required block of protein) and a powerful antioxidant. Taurine “supports neurological development and helps regulate the level of water and mineral salts in the blood” (www.mayoclinic.org). Taurine plays an important role in cardiovascular function by acting not only within the brain but also within peripheral tissues. Taurine acts on GABA receptors; it is commonly supplemented during stress and supports normal relaxation of the arterial muscularis (El Idrissi A. et al. Taurine regulation... AdvExp Med Biol. 2013;775:407-25).

L-Taurine conjugates bile acids, and while unconjugated bile acids are relatively insoluble in water, the conjugated forms with Taurine are much more water soluble and much more able to fulfill their physiologic function of emulsifying fats. This is one of the mechanisms by which taurine gained its reputation for supporting lipid homeostasis.

Grape Seed Extract (95% proanthocyanidins) is amazing for supporting the homeostasis of vasoactivity, along with various organs like the kidney. It is such a potent antioxidant that it is normally associated with numerous health benefits for a multitude of systems. “Grape seed proanthocyanidin extract (GSPE) is known to be an effective natural polyphenol capable of removing free radicals in the body”, and research confirms that it raises activity of antioxidant enzymes and reduces levels of c-reactive proteins, the expression of the cytokineTNF-α, and an intercellular adhesion molecule-1 in the kidney (Bao L. et al. Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats. Mol Med Rep. 2015 Jan;11(1):645-52).

R-Alpha Lipoic Acid is a pure form of alpha lipoic acid and is well known for its remarkable bioavailability. It is excellent support for the body’s organ systems and biochemical pathways, especially the brain, heart, kidneys, blood sugar, pollutant detoxification, and healthy aging.

R-alpha lipoic acid boosts the sirtuin 1 gene that is associated with healthy aging. R-alpha Lipoic acid is an Nrf2 activator. Nrf2 is a potent protein that is present in every cell in the body; however it needs to be “turned on” by an Nrf2 activator. Once it is “turned on”, the Nrf2 activator moves into the cell nucleus and bonds to the DNA, right where the Antioxidant Response Element (ARE) is located. The ARE is the master regulator of the total antioxidant system available in all of the body’s cells (Rücker H, et al…. tuning the Michael acceptor site.Org Biomol Chem. 2015 Jan 26). R-Alpha Lipoic Acid has been identified as a potent booster of glutathione, the major antioxidant in the body (Steele ML. et al. Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells.Redox Biol. 2013 Sep 12;1:441-5).

Catechol-O-Methyltransferase (COMT) is a magnesium-dependent, catecholamine-metabolizing enzyme, which some researchers report that, “In conclusion, the ability of natural mineral-rich waters to increase hepatic COMT activity may eventually explain the positive … effects associated with the consumption of some natural mineral-rich waters (Bastos P et al. Effect of a natural mineral-rich water on catechol-O-methyltransferase function.Magnes Res. 2014 Jul- Sep;27(3):131-41).
Contraindications: None known
Ingredients: Each Tablet Contains: Magnesium (as glycinate) 50 mg. Proprietary blend 550 mg* of: L-Taurine, Grape Seed Extract (95% proanthocyanidins), R-Alpha Lipoic Acid.
Vegetarian: Yes
Suggested Dosage: 1 tablet daily or as directed
Pack: 90 Tablets
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