Product:

Complete Omega 3 Co-Factors

SKU: 1517F
Supportive Function: Co-Factors provide for the proper absorption and utilization of Omega 3 fatty acids. Cofactors also support the heart and the mitochondria, in addition to being an excellent anti-oxidant/aging formula. Take with Complete Omega-3 Essentials 2:1 for best results.

When are Complete Omega 3 Co-Factors helpful? Co-factors help support the absorption and utilization of the fish oils. Additionally, co-factors are necessary for the antioxidant protection of the double bonds in the fish oil and they offer protection against health risk factors.
Clinical Applications Research: Policosanol: A randomized, double blind study was undertaken to compare the efficacy and tolerability of policosanol (10 mg/day) and lovastatin (20 mg/day) in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus. After 6 weeks on a lipid lowering diet, 53 patients were randomized to receive either policosanol or lovastatin tablets that were taken for 12 weeks under double-blind conditions. Both groups significantly (p < 0.001) lowered low-density lipoprotein (LDL)-cholesterol, total cholesterol and the ratio of LDL-cholesterol to high-density lipoprotein (HDL)-cholesterol. Comparison between groups showed that changes in HDL-cholesterol induced by policosanol were significantly greater (p < 0.01) than those induced by lovastatin. Lovastatin significantly (p < 0.05) increased levels of aminotransferase, creatine phosphokinase and alkaline phosphatase. Adverse reactions were more frequent in the lovastatin group (p < 0.01) than in the policosanol group. In conclusion, policosanol administered at 10 mg/day produces more advantageous changes in HDL-cholesterol and has a better safety and tolerability profile than lovastatin 20 mg/day (Crespo N et al. Int J Clin Pharmacol Res 1999; 19(4): 117-27 Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus).

Alpha Lipoic Acid: ALA enhances glucose conversion for cell protection, maintenance, and rebuilding. In diabetes, cells starve from unconverted glucose, resulting in diabetic complications to tissues and organs. Lipoic Acid protects against capillary damage and cataract formation. Lipoic Acid helps regenerate and recycle other antioxidants, especially C, E, and glutathione. It protects against arterial plaque and oxidative damage to LDL cholesterol. It helps neutralize toxins in alcohol and tobacco smoke, mobilize and detoxify heavy metals. Lipoic Acid protects liver from alcohol damage, enhances glucose disposal in adult onset, Type II diabetes, improves insulin sensitivity; and protects against diabetic complications of nerve damage. It has been shown to improve nerve blood flow, reduce oxidative stress, improve distal nerve conduction, and improve reduced levels of deficient glutathione and deficient E in the nerves of diabetics. Lipoic Acid prevents cataracts in animals by increasing levels of C, E, and glutathione in the lens. It binds with the DNA of some viruses and prevents replication. Viral causes are implicated in some cases of diabetes. Supplements have been shown to improve neuropathy and reduce nerve pain. 

Co-Enzyme Q-10: Co-Q-10 is a vitamin-like nutrient that is vital to the production of energy. As one of the electron carriers in the electron transport system, it helps cells utilize oxygen. If you have ever wondered how we get energy from food, or why we have to breathe oxygen, it is because the body strips food of electrons and transports them to an electron acceptor, which is oxygen. Co-Q-10 facilitates this process, providing one of the “spark plugs” for the creation of cellular energy. Without Co-Q-10, we would not have enough energy to fuel the physiological reactions we need to survive (Folkers K & Wolaniuk A. Drugs Exp Clin Res. 1985; 11(8): 539-45). Dr. Folkers notes that Co-Q-10 levels falling to 75% may cause illness, whereas falling to 25% may cause death (Folkers, ibid).
Co-Enzyme Q-10 concentration in the mitochondria (which are sometimes called the “powerhouses” of the cell) is not believed to be saturated, which is one of the reasons researchers think that supplementation is having beneficial effects (Clin Investig 1993; 71(8 Suppl): S66-70). Numerous therapeutic effects of Co-enzyme Q-10 have been reported, most notably in areas where oxygen transport is critical, for instance heart disease, aging and periodontal disease. Since an adequate supply of oxygen is necessary for tissue repair and immune function, many applications have been reported in these areas. Additionally, Co-enzyme Q-10 has therapeutic potential because of its antioxidant properties (fights damaging free radicals). Co-enzyme Q-10 has a wide variety of functions and applications in the body.

Vitamin B-12 (as methylcobalamin) and Folate (as folic acid) are B vitamins associated with lowering homocysteine levels, and hence lowering the risk for complications of high homocysteine levels (heart disease, osteoporosis, placental abruption, weak capillaries, etc.) (Vitamin therapy may reduce hip fracture risk. Folate, B12 appear to reduce homocysteine levels. Health News. 2005 Jun; 11(6): 8).

Glutathione (reduced) is a potent antioxidant, conjugator (detoxer) and cell protector, especially in the liver. Glutathione is most powerful in a reduced or non-oxidized form. Glutathione is a major protector of microglial cells, resident immune cells of the central nervous system. These cells defend the central nervous system against invading microorganisms and clear the debris from damaged cells helping to repair damaged brain cells. (Dringen R. Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal. 2005 Sep-Oct; 7(9-10): 1223-33).

Vitamin C (as ascorbic acid) is an antioxidant, an immune nutrient, a chelator (especially metals), a detoxer, and possesses many healthful characteristics, including an ability to keep glutathione in a reduced form. It has protective qualities, and has been associated in the literature with favorable effects on many conditions, ranging from heart disease (Knekt P et al. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr. 2004 Dec; 80(6): 1508-20). Osteoporosis (Nieves JW. Osteoporosis: the role of micronutrients. Am J Clin Nutr. 2005 May; 81(5): 1232S-1239S) and degenerative joint disease (Goggs R. Nutraceutical therapies for degenerative joint diseases: a critical review. Crit Rev Food Sci Nutr. 2005; 45(3): 145-64). To photoaging and dermatological indications (Farris PK. Topical vitamin C: a useful agent for treating photoaging and other dermatologic conditions. Dermatol Surg. 2005 Jul; 31(7 Pt 2): 814-7; discussion 818), among others.

Magnesium (as chelate) helps calcium absorption, regulates muscle relaxation cycles, and is important as a protective factor in heart disease; magnesium has been described as having an “anti-infarct characteristic” (Ebrahimi S. Anti-infarct effect of magnesium is not mediated by adenosine A1 receptors in rat globally ischaemic isolated hearts. Clin Exp Pharmacol Physiol. 2004 Dec; 31(12): 868-72). Magnesium intake deficiency increases not only vaso-spasms of the coronary artery, but also exacerbates several coronary risk factors such as hypertension, diabetes mellitus, and mental stress (Ueshima K. Magnesium and ischemic heart disease. Clin Calcium. 2005 Feb; 15(2): 175-80). Deficiency also decreases ATPase. It is not unusual for magnesium intake to be below the recommended dietary allowance.
Contraindications: Large amounts of Co-Enzyme Q-10 may interfere with the efficacy of blood thinners, however only small amounts are utilized in this formula.
Ingredients: Vitamin C (as ascorbic acid) 250 mg, Riboflavin 25 mg, Vitamin B-6 (as pyridoxine hydrochloride) 25 mg, Folate (as folic acid) 400 mcg, Vitamin B-12 (as methylcobalamin) 200 mcg, Magnesium (as chelate) 75 mg. Proprietary blend 32.5 mg* of: Glutathione (reduced), Policosanol, Co- Enzyme-Q-10, Alpha Lipoic Acid.
Vegetarian: Yes
Suggested Dosage: 1 tablet daily or as directed
Pack: 60 Tablets
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