Complete K

SKU: 1556
Supportive Function: Essential in directing calcium to the proper tissue, such as bone, and needed as well in the blood coagulation process.

When is Vitamin K helpful? Proper Blood Coagulation, Maintaining Strong Bones and Teeth, Supporting the Cardiovascular System, Blood Sugar and Reducing free radical oxidation.
Clinical Applications Research: Vitamin K is the term given to a group of related compounds. There are three main forms of vitamin K: K1, K2, and K3. There are also subtypes of these different forms of K. Vitamin K1 is found primarily in green leafy vegetables. K2, or menaquinone, is mainly found in the forms of MK4 and MK7. MK4 is primarily found in animal and dairy products, while MK7 is produced by intestinal bacteria and is also found in the Japanese soy product, Natto. K3 is a synthetic form of vitamin K and may have side effects when consumed.

MK7 has been shown to stay in the body longer than other forms of vitamin K. Its half-life is three days, which allows it to build to a more consistent level in the blood stream, in contrast to MK4 or vitamin K1. MK7 is more effective than other forms of vitamin K in both catalyzing osteocalcin carboxylation in bone and in counteracting coumarin anticoagulants in the liver. This is likely due to MK7’s much longer half-life and it’s reported sixfold higher cofactor activity than found in K1. (Schurgers, Leon J., et al. "Vitamin K–containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone- 7." Blood 109.8 (2007): 3279-3283).

Typical diets generally contain up to ten times more K1 than K2, so researchers sometimes dismiss the importance of vitamin K2. These two substances may be better understood as two different vitamins: Whereas K1 is mainly used by the liver to activate blood clotting proteins, K2 is used by other tissues to place calcium in the bones and teeth where it belongs, and keep it out of soft tissues such as joints, arteries and kidneys. Although the body can convert vitamin K1 into vitamin K2, there is evidence suggesting that humans require K2 in the diet for optimal health.

Causes and Symptoms of Deficiency: Inadequate vitamin K levels may result from antibiotic use, vitamin D deficiency, liver damage, chronic alcoholism, or kidney disease. Other causes include intestinal disorders such as celiac disease, cystic fibrosis, or removal of part of the intestines.

Vitamin K has been shown to play a role in:
• Proper blood coagulation
• Maintaining strong bones and teeth
• Supporting the cardiovascular system
• Protecting the brain and other cells against free radical oxidation
• Blood sugar balance

Bone Mineral Density Support: Vitamin K2 has recently gotten a reputation for its role in bone metabolism. Several studies have demonstrated that low dietary vitamin K2 intake is associated with decreased bone mineral density. (Bügel, Susanne. "Vitamin K and bone health." Proceedings of the Nutrition Society 62.04 (2003): 839-843.)

Vitamin K2 may be more effective than K1 in converting the inactive to the active form of glutamate residues involved in bone building.

There is a synergy between the action of vitamin D and vitamin K, particularly in terms of bone strength and cardiovascular health. Vitamin D provides improved bone development by helping you absorb calcium. Vitamin K2 directs the calcium to the bones, while preventing the calcium from being deposited in arteries, joints, and kidneys.

The protein, osteocalcin, is responsible for organizing the deposition of calcium and phosphorus in bones and teeth. Cells produce this protein in the presence of both vitamins A and D, but only when activated by vitamin K. (Oliva A, Ragione FD, Fratta M, Marrone G, Palumbo R, Zappia V. Effect of retinoic acid on osteocalcin gene expression in human osteoblasts. Biochem Biophys Res Commun. 1993; 191(3): 908-14).
Contraindications: Caution is indicated with blood-thinning drugs.
Ingredients: Vitamin K (as K-1 500 mcg, K2-4 1000 mcg, K2-7 200 mcg) 1700 mcg
Vegetarian: Yes
Suggested Dosage: 1 tablet daily or as directed
Pack: 120 Tablets
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